Questions? Call us
+1 (551) 290-3134
THERE'S A REASON WE'RE VOTED THE BEST
Personalized HRT for ,guided by experts.
16M+ prescriptions issued
Over 92% order again
Bioidentical estrogen and progesterone, clinically proven and effective. Prescribed online — no insurance required, no waitlist.
TAKE THE QUIZHSA/FSA eligible • 100% Satisfaction Guarantee**Terms apply
— Introducing Solstice™
Targeted hormone care, personalized to your symptoms
Menopause symptoms often stem from shifting estrogen and progesterone levels. Nurx helps identify what you're experiencing, then connects you with a licensed clinician who can prescribe treatment when appropriate.
Wrinkles
Brain fog
Anxiety
Bloating
Depression
Acne
Painful intercourse
Difficulty exercising
Weight gain
Dry skin
Hair loss
Wrinkles
Brain fog
Anxiety
Bloating
Depression
Acne
Painful intercourse
Difficulty exercising
Weight gain
Dry skin
Hair loss
Bioidentical Estradiol
Helps replace declining estrogen levels to help with night sweats, sleep, mood, and vaginal dryness.
Micronized Progesterone
Helps make estrogen therapy safer for people with a uterus. Included in your plan, if needed.
Topical Vaginal Estrogen
Optional localized treatment that can help with vaginal dryness, discomfort during sex, and urinary symptoms.
— THE PROBLEM
Menopause can manifest as 34 different symptoms. HRT can provide relief across the board.
THE AVERAGE WOMAN ON HRT EXPERIENCES:
80%
fewer hot flashes and night sweats¹
CLINICAL STUDY, PMC 2023
30%
lower risk of Type 2 Diabetes²
PMC CLINICAL STUDY
50%
reduction in heart disease risk³
FDA STATEMENT, 2024
— Timeline
Experience relief across multiple symptoms fast.
Week 2
Improvements in comfort, mood, and sleep
Some women begin noticing improved vaginal comfort, better sleep quality, and emotional balance.
Week 4
Consistent energy & cycle stability
Hormonal shifts may begin to feel more predictable, with fewer energy dips and improved physical stability.
Week 6
Clearer thinking and calmer days
Brain fog, anxious feelings, and mood fluctuations may start to ease as your body continues adjusting.
Week 8
Feeling more like yourself again
Many women report feeling more balanced, comfortable, and in tune with their body by this stage.
— Introducing
Solstice™: The All-in-One HRT system.
Our personalized treatment addresses the root causes of all menopause symptoms.
As needed dose adjustments
Personalized ratios to minimize side effects
Unlimited clinical support
100% Satisfaction Guaranteed*
Maintaining Quality & Excellence
— PERSONALIZATION DONE RIGHT
Don't fall for "one-size-fits-all" solutions. Your hormones are unique to you and deserve personalization.
Many HRT treatments only offer one-size-fits-all solutions, forcing you into potentially incorrect hormonal ratios. With Solstice™, you can adjust the ratios of estrogen and progesterone to ensure your hormones stay in balance.
Solstice™: The Personalized HRT system
Fully personalized treatment that can be adjusted at any time with clinical guidance.
Other Treatments:
One-Size-Fits-All
Fixed ratios, liable to cause hormonal imbalance in some women.
2 MINUTES · NO INSURANCE NEEDED
— REAL REVIEWS
Over 2M+ women have trusted us with their health. Here's what they have to say:
Excellent 4.7They make it easy...
“They make it easy to have your questions answered and review all the information.”
Yulisa Sanchez
Verified User
5/21/2026
Very quick message response....
“Very quick message response. Always very helpful and friendly!”
Dawn Johnson
Verified User
5/18/2026
No hassle...
“No hassle, fast shipments, have literally worked faster than local doctors.”
Gabriela Garza
Verified User
5/15/2026
Fantastic communication...
“Fantastic communication with providers. Promt and effecient services and reasonable fees. Its helped change my life for the better!”
Desiree Layman
Verified User
5/14/2026
Love nurx...
“Love nurx, so simple and inexpensive, The way it should be!!! I recommend it to everyone!”
Lindsey Williams
Verified User
5/12/2026
So easy...
“So easy, fast, private. Healthcare made easy in a busy life.”
Denise Kaufman
Verified User
5/11/2026
They make it easy...
“They make it easy to have your questions answered and review all the information.”
Yulisa Sanchez
Verified User
5/21/2026
Very quick message response....
“Very quick message response. Always very helpful and friendly!”
Dawn Johnson
Verified User
5/18/2026
No hassle...
“No hassle, fast shipments, have literally worked faster than local doctors.”
Gabriela Garza
Verified User
5/15/2026
Fantastic communication...
“Fantastic communication with providers. Promt and effecient services and reasonable fees. Its helped change my life for the better!”
Desiree Layman
Verified User
5/14/2026
Love nurx...
“Love nurx, so simple and inexpensive, The way it should be!!! I recommend it to everyone!”
Lindsey Williams
Verified User
5/12/2026
So easy...
“So easy, fast, private. Healthcare made easy in a busy life.”
Denise Kaufman
Verified User
5/11/2026
— GET STARTED
What used to cost $1,800/mo. can now be started for as low as $65/mo.
Trying to relieve symptoms on your own without HRT is expensive and less effective than clinical treatment.
Managing symptoms without HRT:
- Specialist Doctors Visit-$250
- Lab Testing-$400
- Botox-$400
- Weight Loss Injections-$250
- Gut & Vaginal Probiotics-$180
- Skincare-$100
- Lubrication Suppositories-$90
- Hair Loss Supplements-$80
- Sleep & Stress Supplements-$50
- Total=-$1,800
Starting at $65/mo
Ready to experience relief? Get your personalized plan today.
Solstice™ All-in-1 HRT System Includes:
Bioidentical Estrogen
Daily Progesterone Capsules
On-Time Refills Guaranteed*
Always on Clinical Assistance via Messaging
100% Satisfaction Guarantee*
100% U.S. Based Care Agents
100% satisfaction guaranteed*
HSA/FSA eligible care
Free & fast shipping
— 3 SIMPLE STEPS
Reviewed in 24 hours. Shipped quickly after approval.
Select your treatment
Choose between form factors and add-ons tailored to fit your symptoms, with approval of your clinician.
Get clinical approval & receive your shipment
Discuss any needs with a specialist to ensure treatment is right for you.
Message clinician anytime
Dose tweaks, refills, questions — same-day reply most of the time.
Get started with
everything you need.
Personalized hormone care from home, prescribed by a licensed clinician based on your symptoms, health history, and goals.
Bioidentical hormones
Personalized treatment plan
Ongoing support
Delivered to your door
— Contact Us
You ask. We answer.
Have more questions? Reach out to our team.
+1 (551) 290-3134
7 DAYS A WEEK · 8AM – 8PM ET
nurx-support@thirtymadison.com
SECURE MESSAGE
In-portal, Encrypted
AVERAGE REPLY
Under 1 hour